Bills vs. Rams: Game day info, betting spread, and how to watch

(Photo by Timothy T Ludwig/Getty Images)
(Photo by Timothy T Ludwig/Getty Images) /

Here we are just hours from the LA Rams’ first game of the 2022 NFL season, and we are no closer to knowing what to expect than at the beginning of training camp. Frustrating? You bet it is. But we can take comfort in the knowledge that what we don’t know, the Buffalo Bills have no way to know either.

And so, here we are, twiddling our thumbs, awaiting the opening kickoff. Why not make use of the available time? To help you out, here are some of the key facts you may need, whether you are betting on the game, deciding who to sit and who to play in your first week of fantasy football, or simply looking for more information to give a better appreciation for the game.

The Buffalo Bills and LA Rams are two of the NFL’s favored teams to compete in the NFL Championship Game this year, leading some to tout this one as a Super Bowl LVII preview.

What do we know about the Rams for this one? We know that the team has plenty of smoldering confidence in this one. And that should get an emotional boost as the Rams unfurl their NFL Championship banner in the pregame ceremony.

LA Rams Injury Report vs Bills Week 1


  • WR Van Jefferson (Knee) – Out


  • OT Tommy Doyle (Foot) – Questionable
  • TE Quentin Morris (Hamstring) – Questionable


Bills vs Rams Betting Odds, Spread, Over/Under & Betting Pick Week 1

We used WynnBET to find the latest odds and spread for this one.

Point Spread

  • Bills -2.5 (-110)
  • Rams +2.5 (-110)

Money Line

  • Bills -140
  • Rams +115

Over/Under – 52.0 points

  • Over -110
  • Under -110

Recommended Bets:

I love the LA Rams as home underdogs, and the raw emotions that will be running through this team in this game will bury the needle at optimal play. As well as the Bills will play this season, I don’t see them overcoming the red hot Rams, particularly when they face a team that has, in many ways, already faced a bit of disrespect despite winning it all just months ago.

I like the Rams’ offense to do just enough to put points on the board. And a fully healthy and revitalized DB Jalen Ramsey to lead the defense to keep the Bills from keeping pace.

Oh, and look for ILB Bobby Wagner to put up some plays worthy of an NFL highlight reel.

If you want the full game breakdown, just click this LINK HERE.

Take the Rams and the points (+2.5) in this one
Take the Rams on the Moneyline (+115) to win outright
Take the OVER at 52.0.5 (-110) in this one
National broadcast: FOX Sports

Whether or not you place a bet, you will undoubtedly be in for a thriller in this one

What TV Channel is the Bills vs Rams Game On For Week 1?

This game is the second game to be broadcast by NBC Sports and will air at 5:2o pm PT/8:20 pm ET.

Bills vs Rams Week 1 Game Live Stream

You can catch the action from this game live by streaming on Fubo TV.

Rams Next Game and Schedule

The LA Rams will travel to face the Atlanta Falcons (0-0) in Week 2 on Sunday, September 18, 2022, at 1:05 pm PT. The Buffalo Bills will host the Tennessee Titans (0-0) on Monday, September 19, 2022, at 4:15 pm PT.

Trending. Can the LA Rams extend their Week 1 winning streak?. light