Los Angeles Rams tabbed as top Week 4 upset pick by NFL betting expert

BetSided NFL betting expert Iain MacMillan expects the Rams and their passing game to win out in Indianapolis.

Los Angeles Rams quarterback Matthew Stafford (9)
Los Angeles Rams quarterback Matthew Stafford (9) / Kareem Elgazzar/The Enquirer / USA TODAY

On Monday Night Football, the Los Angeles Rams weren’t able to get the win, but they were able to get a backdoor push as three-point underdogs to the Cincinnati Bengals. Now, BetSided's NFL betting expert Iain MacMillan thinks that the Rams could pull off an upset win against the Indianapolis Colts in Week 4. 

Each week, MacMillan picks every game of the NFL schedule in his “Road to 272 Bets” and this week he likes the Rams as an underdog. The Colts are riding high at 2-1 after beating the Ravens in Baltimore. 

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Rams vs. Colts odds, spread and total

Betting expert for Rams in Week 4

One of the biggest strengths of the Colts is their run defense, but that won’t be too help against the Rams. Matthew Stafford will be dropping back a lot and BetSided NFL betting expert Iain MacMillan thinks that is bad news for Indy. 

“Where they struggle is their secondary, giving up 6.8 yards per pass attempt, which ranks 23rd in the NFL. That's going to be an issue when they face the Rams in Week 4, who rely almost solely on their passing game to get things done.”

2-1 is a good start to the year for Indianapolis, especially with one of those wins coming without Anthony Richardson. However, this might just be a good start, not a good season. 

“It might be time to sell high on this Colts team after two straight wins. I still believe the Rams are a better team than people thought they'd be this season.”

Take the Rams on the moneyline in Week 4. 

Follow all Iain MacMillan’s bets HERE

Game odds refresh periodically and are subject to change